A newly identified protein can be manipulated to make opioid painkillers effective at lower doses while also muting the reward mechanism that leads to addiction, Mount Sinai researchers have found.
Feb 12, 2018
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New research led by investigators at Massachusetts General Hospital (MGH) provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances.
Apr 3, 2021
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The herb kratom is increasingly being used to manage pain and treat opioid addiction, but it's not safe to use as an herbal supplement, according to new research led by faculty at Binghamton University, State University of ...
Jul 9, 2019
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A new study led by UC San Francisco scientists shows that brain cells, or neurons, react differently to opioid substances created inside the body - the endorphins responsible for the "natural high" that can be produced by ...
May 10, 2018
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Fentanyl, oxycodone, morphine—these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.
Apr 24, 2021
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Investigators at the Stanford University School of Medicine and their collaborators at three other institutions have identified a novel compound that appears to exhibit painkilling power comparable to morphine but lacks that ...
Aug 17, 2016
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With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.
Aug 29, 2018
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Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signals that travel ...
Jul 5, 2012
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Scientists at the Stanford University School of Medicine have discovered that ketamine works as an antidepressant at least in part by activating the brain's opioid system.
Aug 29, 2018
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Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer side effects, ...
Jun 15, 2020
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