There's been a recent push in the U.S. to make naloxone—a fast-acting opioid antidote—available without a prescription. This medication has saved lives, but it's less effective against powerful synthetic opioids, such ...
Mar 28, 2023
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Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells like those in our bodies are able to build up resistance to opioid pain drugs within hours. Humans have known about the ...
Apr 3, 2012
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Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive. For decades, scientists have attempted to develop drugs that selectively activate one type of opioid receptor ...
May 3, 2023
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At a hearing on Capitol Hill earlier this year, U.S. Senator Lamar Alexander asked an important question: Why is most of the treatment for opioid addiction more opioids?
Jun 27, 2018
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It's long been known that opioid overdose deaths are caused by disrupted breathing, but the actual mechanism by which these drugs suppress respiration was not understood. Now, a new study by Salk scientists has identified ...
Aug 13, 2021
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A new approach to treating neuropathic pain is making a key step forward thanks to researchers at The University of Texas at Austin.
Jan 30, 2024
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New research may help explain why drug treatments for addiction and depression don't work for some patients.
Sep 2, 2015
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The annual cost of chronic pain in the United States is estimated to be more than $635 billion in direct medical costs, lost productivity and disability programs. One in five adults—50 million Americans—report living ...
Jul 10, 2019
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Opioids are the most powerful painkillers. Researchers at the Charité - Universitätsmedizin Berlin have now found that the analgesic effects of opioids are not exclusively mediated by opioid receptors in the brain, but ...
Jan 17, 2017
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Approximately three million Americans suffer from opioid use disorder, and every year more than 80,000 Americans die from overdoses. Opioid drugs, such as heroin, fentanyl, oxycodone and morphine, activate opioid receptors. ...
Feb 18, 2023
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