Medical research

New study delivers road map of lung development

Researchers have compiled the most comprehensive road map of the protein composition of human lungs, providing a clearer picture of the healthy development of this essential organ that made terrestrial life possible.

Surgery

Increasing organ donation by increasing consent to donate

When seeking consent for organ donations, in-person requests made to substitute decision-makers, with physician involvement, are more likely to result in a positive response, according to a study of organ donation in Ontario, ...

Medical research

Study pinpoints molecular targets of transplant rejection

Researchers from the University of Sydney and Monash University have made a significant discovery that uncovers what is happening at the molecular level when an organ transplant is recognized as foreign by the immune system.

Immunology

What does it mean to be 'immunocompromised?'

Throughout the COVID-19 pandemic, there have been countless news reports identifying one group of individuals as being particularly vulnerable to the virus: the immunocompromised.

Oncology & Cancer

Cancer shortens lifespan in transplant recipients

People who have received organ transplants face an elevated risk of developing cancer, primarily due to immunosuppression from medications to prevent organ rejection, as well as underlying medical conditions. An important ...

Other

Sanofi buys US biotech firm in acquisition spree

French pharmaceutical giant Sanofi announced on Wednesday its second acquisition of a US firm in as many months, buying transplant drug company Kadmon for $1.9 billion (1.6 billion euros).

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Organ transplant

Organ transplant is the moving of an organ from one body to another (or from a donor site on the patient's own body), for the purpose of replacing the recipient's damaged or failing organ with a working one from the donor site. Organ donors can be living or deceased (previously referred to as cadaveric).

Organs that can be transplanted are the heart, kidneys, liver, lungs, pancreas, penis, and intestine. Tissues include bones, tendons, cornea, heart valves, veins, arms, and skin.

Transplantation medicine is one of the most challenging and complex areas of modern medicine. Some of the key areas for medical management are the problems of organ rejection - where the body has an immune response to an organ which causes failure of the transplant and of ensuring that the organ can be kept in a functioning state while it is transplanted from one body to another. This is a very time sensitive process.

In most countries there is a shortage of suitable organs for transplantation. Countries often have formal systems in place to manage the allocation and reduce the risk of rejection. Some countries are associated within international organisations like Eurotransplant in order to increase the supply of appropriate donor organs and the organ recipients.

Transplantation also raises a number of bioethical issues, including the definition of death, when and how consent should be given for an organ to be transplanted and payment for organs for transplantation.

This text uses material from Wikipedia, licensed under CC BY-SA