Diseases, Conditions, Syndromes

Osteoporosis-treated adults have elevated risk of mortality

(HealthDay)—Women and men below age 70 who are treated for osteoporosis have an excess mortality risk, according to a study published online Feb. 7 in the Journal of Bone and Mineral Research.

Health

Exercise, not vitamins, urged to prevent falls in seniors

Falling is the leading cause of injury-related death among people over age 65, and seniors who want to avoid falls should exercise, not rely on supplements like vitamin D, US guidelines said Tuesday.

Diseases, Conditions, Syndromes

Finding the right osteoporosis medication

Dear Mayo Clinic: The bisphosphonate drugs I take for osteoporosis aren't working in my case. My doctor has suggested a few alternatives. Any thoughts on what might be best?

Diseases, Conditions, Syndromes

How a Mediterranean diet could reduce osteoporosis

Eating a Mediterranean-type diet could reduce bone loss in people with osteoporosis—according to new research from the University of East Anglia.

Genetics

A new 'atlas' of genetic influences on osteoporosis

A ground-breaking new study led by researchers from the Lady Davis Institute (LDI) at the Jewish General Hospital (JGH) has succeeded in compiling an atlas of genetic factors associated with estimated bone mineral density ...

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Osteoporosis

Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture. Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal disorders and other chronic diseases or as a result of medications, specifically glucocorticoids, when the disease is called steroid- or glucocorticoid-induced osteoporosis (SIOP or GIOP). Given its influence is the risk of fragility fracture, osteoporosis may significantly affect life expectancy and quality of life.

Osteoporosis can be prevented with lifestyle changes and sometimes medication; in people with osteoporosis, treatment may involve both. Lifestyle change includes preventing falls and exercise; medication includes calcium, vitamin D, bisphosphonates and several others. Fall-prevention advice includes exercise to tone deambulatory muscles, proprioception-improvement exercises; equilibrium therapies may be included. Exercise with its anabolic effect, may at the same time stop or reverse osteoporosis.

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