Oncology & Cancer

FAK protein linked to chemotherapy resistance in ovarian cancer

Although the number of women being diagnosed and dying of ovarian cancer is declining, recurrence, drug resistance and mortality remain high for women with high-grade serous ovarian carcinoma, the most common form of epithelial ...

Oncology & Cancer

Novel therapy studied for inherited breast cancer

UT Health San Antonio researchers have discovered a novel way to kill cancers that are caused by an inherited mutation in BRCA1, the type of cancer for which actress Angelina Jolie had preventive double mastectomy and reconstructive ...

Oncology & Cancer

Addicted to ran, ovarian cancer cells stop moving when deprived

Did you know that 90% of cancer patients die from distant metastasis? The latter occurs when cancer cells have the ability to move within the patient's body and invade its healthy tissues. In a study published in Nature Communications, ...

Oncology & Cancer

Targeting stem-like cells could prevent ovarian cancer recurrence

Ovarian cancer is not the most common form of cancer, but it's among the deadliest. That's because about 70 percent of cases recur. A new study by researchers at the University of Pittsburgh, UPMC Hillman Cancer Center, Magee-Womens ...

Oncology & Cancer

New drug targets for BRCA-driven cancer uncovered

BRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes have up to an 80 percent risk of developing breast cancer and a 50 percent risk of developing ovarian ...

Oncology & Cancer

Ovarian cancer genetics unravelled

Patterns of genetic mutation in ovarian cancer are helping make sense of the disease, and could be used to personalise treatment in future.

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