Medications

New powerful painkiller has abuse experts worried

Drug companies are working to develop a pure, more powerful version of the nation's second most-abused medicine, which has addiction experts worried that it could spur a new wave of abuse.

Medications

OxyContin formula change has many abusers switching to heroin

A change in the formula of the frequently abused prescription painkiller OxyContin has many abusers switching to a drug that is potentially more dangerous, according to researchers at Washington University School of Medicine ...

Medications

Sugar in the diet may increase risks of opioid addiction

Could a diet high in refined sugars make children and adults more susceptible to opioid addiction and overdose? New research, from our laboratory of behavioral neuroscience at the University of Guelph, suggests it could.

Medications

Sales of oxycodone by doctors fall in Florida

The number of oxycodone pills sold by Florida doctors dropped dramatically in 2011, following a series of high-profile arrests and a legislative crackdown on the storefront "pill mills" that made South Florida the hub of ...

Medical research

Opiates' side effects rooted in patients' genetics, study shows

Genetics play a significant role in determining which patients will suffer the most from the disturbing side effects of opiates, commonly prescribed painkillers for severe to moderate pain, according to a new Stanford University ...

Medical research

A path to lower-risk painkillers

For patients managing cancer and other chronic health issues, painkillers such as morphine and Vicodin are often essential for pain relief. The body's natural tendency to develop tolerance to these medications, however, often ...

Health

Friends and family enable most opioid abusers

(Medical Xpress) -- A new study by Yale School of Medicine reveals that nearly one third of those who use opioids for non-medical reasons obtain these drugs directly from physicians, but the majority get them from friends ...

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Oxycodone

Oxycodone is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine (heroin), and codeine.

Oxycodone oral medications are generally prescribed for the relief of moderate to severe pain. Currently it is formulated as single ingredient products or compounded products. Some common examples of compounding are oxycodone with acetaminophen/paracetamol or NSAIDs such as ibuprofen. The formulations are available as generics but are also made under various brand names. OxyContin is Purdue Pharma's brand for time-release oral oxycodone. The manufacturing rights to time-released generic oxycodone are under dispute.

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