Many doctors, researchers and patients are eager to take advantage of the promise of stem cell therapies to heal damaged tissues and replace dysfunctional cells. Hundreds of ongoing clinical trials are currently delivering ...
Jan 22, 2018
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Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal of Cell Biology, suggests ...
Dec 21, 2017
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Tumor protein p53 is one of the most critical determinants of the fate of cancer cells, as it can determine whether a cell lives or dies in response to stress. In a new study published today in the journal Nature Communications, ...
Dec 13, 2017
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A Keck School of Medicine of USC research team has identified how cancer stem cells survive. This finding may one day lead to new therapies for liver cancer, one of the few cancers in the United States with an incidence rate ...
Oct 12, 2017
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There are two important categories of genes involved in cancer development, oncogenes and tumor suppressor genes. When oncogenes gain function, e.g. through mutation, they actively promote cancer - drugs that turn them off ...
Oct 10, 2017
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Cancer researchers have long hailed p53, a tumor-suppressor protein, for its ability to keep unruly cells from forming tumors. But for such a highly studied protein, p53 has hidden its tactics well.
Oct 9, 2017
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A study that teases apart the biological mechanisms by which human papillomaviruses (HPV) cause cancer has found what researchers at Georgetown University Medical Center say is a new strategy that might provide targeted treatment ...
Oct 2, 2017
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Nasopharyngeal carcinoma (NPC) is a common epithelial squamous cell head and neck cancer which is strongly associated with gamma herpes Epstein-Barr virus infection and the intake of salted fish. NPC incidence remain significantly ...
Aug 23, 2017
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The gene p53 functions normally as a cancer suppressor, but mutated versions of the gene have been implicated in the development and growth of nearly half of all human cancers. Now, for the first time, scientists at VCU Massey ...
Jun 14, 2017
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Directly injecting a tumor with an agent that activates a natural, powerful tumor suppressor enhances the drug's capacity to attack the tumor both locally and where it spreads, scientists report in the journal Cancer Research.
May 22, 2017
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