A newly identified protein can be manipulated to make opioid painkillers effective at lower doses while also muting the reward mechanism that leads to addiction, Mount Sinai researchers have found.
Feb 12, 2018
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New research led by investigators at Massachusetts General Hospital (MGH) provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances.
Apr 3, 2021
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This is big news for Irritable Bowel Syndrome (IBS) patients: 11 percent of the world's population suffers from IBS, but the fight against chronic pain has taken a major step forward with scientists identifying receptors ...
Oct 16, 2019
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Fentanyl, oxycodone, morphine—these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.
Apr 24, 2021
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With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.
Aug 29, 2018
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Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer side effects, ...
Jun 15, 2020
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The menopause transition is associated with several health issues. The incidence of both sleep apnea and joint pain, for example, are higher in postmenopausal women. A new study aimed to investigate the association between ...
Mar 2, 2022
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A team of researchers from Université Paris-Saclay and Université Paris Descartes has developed a nano-drug that has been found to reduce pain in rodents. In their paper published in the journal Science Advances, the group ...
Researchers from Monash University have developed a new drug delivery strategy able to block pain within the nerve cells, in what could be a major development of an immediate and long lasting treatment for pain.
May 31, 2017
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A brain region controlling whether we feel happy or sad, as well as addiction, is remodeled by chronic pain, reports a new Northwestern Medicine study.
Dec 21, 2015
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