Opioid receptors are proteins in the central nervous system that are targeted by opioid drugs for pain relief. There are three subtypes of opioid receptors, MOP, DOP and KOP, in addition to the opioid-related NOP receptor.
A newly identified protein can be manipulated to make opioid painkillers effective at lower doses while also muting the reward mechanism that leads to addiction, Mount Sinai researchers have found.
Feb 12, 2018
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(Medical Xpress)—Imagine that your doctor knows from evidence-based studies that if he tells you about certain, small side-effects to a particular drug, you are significantly more likely to experience that side effect than ...
Activity in a brain area known as the dorsal posterior insula is directly related to the intensity of pain, a brain imaging study of 17 people has found.
Mar 9, 2015
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In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.
Aug 14, 2012
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Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, ...
Apr 9, 2024
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Research from Nottingham University Business School is one step closer to helping to predict deaths from respiratory diseases by analyzing the shopping habits of customers in local authority areas across England.
Nov 22, 2023
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A compound—one of 27 million screened in a library of potential new drugs—reversed four types of chronic pain in animal studies, according to new research led by NYU College of Dentistry's Pain Research Center and published ...
Nov 13, 2023
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A new study in JAMA Network Open may provide key answers to how to help people experiencing chronic back pain.
Sep 28, 2023
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The opioid epidemic in the United States has exacted an incalculable toll on individuals and communities, creating an urgent need for alternative painkillers. The search for non-opioid treatments is crucial, not only to mitigate ...
Sep 20, 2023
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