Health

Menopause symptoms nearly double the risk of chronic pain

In addition to the other health conditions affected by estrogen, it has also been shown to affect pain sensitivity. This finding was the basis of a study of more than 200,000 records from the Veterans Health Administration ...

Neuroscience

Microglia transmit pain to the brain during stress

Research in male mice published in JNeurosci demonstrates activation of microglia in the spinal cord is responsible for increased pain sensitivity in response to stress.

Diseases, Conditions, Syndromes

Why do some people hurt more than others?

Anyone who came of age in the 1990s remembers the "Friends" episode where Phoebe and Rachel venture out to get tattoos. Spoiler alert: Rachel gets a tattoo and Phoebe ends up with a black ink dot because she couldn't take ...

Neuroscience

People with fibromyalgia have inflammation of the brain

The causes of the difficult-to-treat pain syndrome fibromyalgia are largely unknown. Using PET brain imaging, researchers at Karolinska Institutet and Massachusetts General Hospital have now shown that glial cells – the ...

Neuroscience

Altered pain processing after opioid discontinuation

An imaging study of the brain and spinal cord published in JNeurosci reveals pain processing changes in healthy men after receiving a short-term application of a strong opioid. The research provides a plausible mechanism ...

Neuroscience

Understanding pain exacerbation with opioid use

A new study published in JNeurosci advances understanding of how the potent opioid analgesic fentanyl can increase pain sensitivity in animals. These findings could inform the development of treatments for chronic pain that ...

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