Diabetes

Discovery paves the way for earlier detection of type 1 disease

Type 1 diabetes, an autoimmune disease that typically emerges before the age of 20, wipes out the body's ability to produce insulin—a hormone that's essential to life. Diagnosis often comes after symptoms arise, at which ...

Diabetes

Cellular sickness linked to type 1 diabetes onset

A UC San Francisco study of human and mouse pancreatic tissue suggests a new origin story for type 1 (T1) diabetes. The findings flip current assumptions about the causes of the disease on their head and demonstrate a promising ...

Medical research

Weight loss surgery changes the way our bodies sense food

How bariatric surgery helps people with obesity and diabetes is related to changes in the way the gut senses food and nutrients after the operation, researchers report February 5 in the journal Cell Reports. They found that ...

Medical research

Functional insulin-producing cells grown in lab

UC San Francisco researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes.

Medical research

How type 1 diabetes gradually destroys insulin production

Using the new Imaging Mass Cytometry method, researchers of UZH have investigated the pancreas of healthy organ donors and those with type 1 diabetes. The study shows that many beta cells, which normally produce insulin, ...

Medical research

Next step toward replacement therapy in type 1 diabetes

Scientists have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very mobile and that their destiny is strongly influenced by their immediate environment. ...

Diabetes

Diabetes results from a breakdown of epigenetic control

Diabetes affects more than 400 million individuals worldwide. In what is becoming a paradigm shift, researchers have begun to find that the disease may result in part through pancreatic beta cells losing their functional ...

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