A panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of Science Translational Medicine.
Sep 8, 2023
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Atopic dermatitis (AD) in adulthood is associated with an increased risk for venous thromboembolism (VTE), according to a study published online May 31 in JAMA Dermatology.
Jun 1, 2023
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How close a person lives to a major road could have an impact on their eczema risk.
Feb 15, 2023
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Irritable bowel syndrome (IBS) is a difficult disease to treat, characterized by chronic abdominal pain related to bowel movements, of which there are four types: diarrheal, constipation, mixed, and unclassifiable. Patients ...
Jan 12, 2023
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(HealthDay)—There is a bidirectional association between anxiety and depression and migraine and tension-type headache (TTH), according to a study published online Jan. 21 in The Journal of Headache and Pain.
Feb 7, 2022
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Vascular calcification, low bone mass and fragility fractures are all frequent age-dependent disorders. Recent clinical and experimental data suggest that vascular calcification and bone loss could share pathophysiological ...
Nov 15, 2021
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Gut microbiota-derived metabolites play important roles in health and disease. In this study, we show the pathophysiological role of D-serine in association with the gut microbiota in humans and mice with acute kidney injury. ...
Nov 27, 2018
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A new British Journal of Pharmacology review examines how phosphodiesterase-5 (PDE5) inhibitors, which were originally approved to treat erectile dysfunction, are finding clinical uses for a wide variety of conditions.
Apr 19, 2018
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A well-known rheumatoid arthritis medication containing the active agent adalimumab, a therapeutic human monoclonal antibody, is also effective for treating non-infectious uveitis, a rare eye disease. This has now been discovered ...
Oct 10, 2016
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Botond Roska and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) implicate a clearly defined neuron type and its circuit in the retina in the pathophysiology of idiopathic congenital nystagmus. ...
Jan 5, 2016
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Pathophysiology is the study of the changes of normal mechanical, physical[disambiguation needed ], and biochemical functions, either caused by a disease, or resulting from an abnormal syndrome. More formally, it is the branch of medicine which deals with any disturbances of body functions, caused by disease or prodromal symptoms.
An alternative definition is "the study of the biological and physical manifestations of disease as they correlate with the underlying abnormalities and physiological disturbances."
The study of pathology and the study of pathophysiology often involves substantial overlap in diseases and processes, but pathology emphasizes direct observations, while pathophysiology emphasizes quantifiable measurements.
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