Much evidence exists to show that in humans, oral inflammatory conditions such as periodontal disease can affect overall health. In its later stages, periodontal disease can lead to systemic issues such as cancer, cardiovascular ...
Prof. Gabriel Nussbaum and his team at the Institute of Biomedical and Oral Research, Hebrew University-Hadassah Faculty of Dental Medicine, have recently published research in the journal Gut that uncovers a pivotal link ...
Mar 26, 2024
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Researchers from Niigata University and a University of Pennsylvania team have identified a novel macrolide–DEL-1 axis that helps in bone regeneration and new bone formation. This finding may lead to the development of ...
Jan 25, 2024
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Although most people don't associate oral disease with serious health problems, increasing evidence shows that oral bacteria play a significant role in systemic diseases like colon cancer and heart disease. Now, new research ...
Jul 10, 2023
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Researchers at NYU College of Dentistry have developed a single score to describe the level of cytokines in saliva, and this score is linked with the severity of clinical gum inflammation, according to a study published in ...
Feb 15, 2023
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A topical gel that blocks the receptor for a metabolic byproduct called succinate treats gum disease by suppressing inflammation and changing the makeup of bacteria in the mouth, according to a new study led by researchers ...
Sep 20, 2022
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A new University of Florida study has found that bacteria in the saliva of college students who reported recent thoughts of suicide differed in significant ways from those found in students who had not experienced recent ...
Aug 25, 2022
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Researchers from the University of Louisville School of Dentistry and their colleagues have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the ...
Jan 5, 2022
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Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part ...
Dec 23, 2021
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In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens ...
Jan 11, 2021
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Periodontitis (peri = around, odont = tooth, -itis = inflammation) refers to a number of inflammatory diseases affecting the periodontium — that is, the tissues that surround and support the teeth. Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. Periodontitis is caused by bacteria that adhere to and grow on the tooth's surfaces, along with an overly aggressive immune response against these bacteria. A diagnosis of periodontitis is established by inspecting the soft gum tissues around the teeth with a probe and radiographs by visual analysis, to determine the amount of bone loss around the teeth. Specialists in the treatment of periodontitis are periodontists; their field is known as "periodontology" and "periodontics".
Chronic Periodontitis, the most common form of the disease, progresses relatively slowly and typically becomes clinically evident in adulthood. Aggressive Periodontitis is a rarer form, but as its name implies, progresses more rapidly and becomes clinically evident in adolescence. Although the different forms of periodontitis are all caused by bacterial infections, a variety of factors affect the severity of the disease. Important "risk factors" include smoking, poorly-controlled diabetes, and inherited (genetic) susceptibility.
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