Immunology

How dying cells prevent dangerous immune reactions

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues. Scientists from the German Cancer Research Center have now identified a receptor on murine ...

Medical research

Metabolic adaptation ensures survival of colon cancer cells

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often ...

Medications

New diagnostic approach rapidly identifies the right antibiotics

Patients with bacterial infections who are promptly diagnosed and treated with the most effective antibiotic fare better than those who wait. But current methods of identifying which drug will kill the pathogen take days ...

Medical research

Studying the human brain in mice

The human brain is a tricky study subject. Brain scans are still limited in resolution and the knowledge they can provide, and in vitro approaches are not yet able to fully replicate the important micro-environment of brain ...

Immunology

When studying immune cells, environment matters

For years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report in Immunity suggests looking outside the dish and into living organisms gives a drastically ...

Medical research

No bones about it, this protein slows down fracture-healing

Broken bones are a bigger deal the older you are: even after they've healed, the bones of older people are weaker and more likely to re-fracture. And since more than 6 million Americans break a bone each year, figuring out ...

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