Researchers from GeneDx have published a paper titled "Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes" in Nature Methods. The work details ...
Jun 26, 2023
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Regeneration in the CNS is a rare event and strongly limited to the replacement of so-called oligodendroglial cells and their electrically insulating elements of the axons, called myelin sheaths. This is also true for multiple ...
Aug 25, 2022
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Copper is essential for many cellular functions, including cellular respiration, antioxidant defense, neurotransmitter biosynthesis and neuropeptide amidation, among others. Until recently, only two inborn errors of copper ...
Aug 18, 2022
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A team of researchers from the Department of Veterans Affairs, Oak Ridge National Laboratory, Harvard's T.H. Chan School of Public Health, Harvard Medical School and Brigham and Women's Hospital has developed a novel, machine ...
Apr 28, 2022
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Three newly-defined phenotypes (observable characteristics or traits for an individual) that capture genetic associations which may provide protection against SARS-CoV-2, are presented in a study published in Nature Genetics. ...
Apr 12, 2022
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Cancer stem cells (CSCs), a key driver behind malignant cancer progression, are self-renewing, highly metastatic and therapeutically resistant. As cancer progresses, cancer cells display a phenotypic plasticity between the ...
Apr 1, 2022
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A new study has revealed detailed information on the various ways patients with multiple sclerosis (MS) become disabled, analyzing both the role of relapses on long-term outcomes and the role of worsening that occurs independent ...
Feb 14, 2022
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High altitude environments are one of the most demanding habitats in which humans have ever lived. This difficulty is mainly due to hypoxia: oxygen is less available to human tissues at high altitude. However, several populations ...
Jul 21, 2021
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Approximately one in four patients hospitalized for the acute respiratory distress syndrome (ARDS) associated with severe COVID-19 infections may have a distinct phenotype (disease presentation) or biochemical profile associated ...
Apr 15, 2021
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A new study in the Journal of Biomedical Informatics uses machine learning on unlabeled electronic health record (EHR) data to shed light on the emergence of cardiovascular disease (CVD).
Oct 11, 2019
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