Cardiology

Specific phenotype relevant in subclinical primary aldosteronism

(HealthDay)—A suppressed renin phenotype is associated with higher incidence of incident hypertension than other plasma renin activity (PRA) phenotypes, according to a study published online Oct. 9 in the Annals of Internal ...

Health

Questionnaire-based approach valid for identifying frailty

(HealthDay)—A questionnaire-based approach seems to be valid for identifying adults in the intensive care unit with a frailty phenotype, according to a study published online March 30 in the Annals of the American Thoracic ...

Diseases, Conditions, Syndromes

'GOLD' criteria may misdiagnosis normal phenotypes

(HealthDay)—The Global Lung Initiative (GLI)-defined normal spirometry includes adjusted mean values in the normal range for multiple phenotypes, even when classified as respiratory impairment by Global Initiative for Chronic ...

Medical research

Study explores in vivo role of ubiquinone in mouse model

(HealthDay)—Ubiquinone (UQ) does not act as an antioxidant in vivo, and partial restoration of UQ levels and mitochondrial function can reverse severe disease phenotypes and shortened lifespan, according to an experimental ...

Genetics

Focusing in on high-resolution network biology

A central challenge in genetics is to understand how changes in DNA result in observable changes in an organism; how genotype maps to phenotype. As genes and their protein products do not act in isolation, connecting genotype ...

page 5 from 10