Medical research

Making bones is less difficult than was previously thought

The way in which bone formation occurs needs to be redefined. This was revealed by Radboud university medical center researchers and their colleagues in a publication in Nature Communications. It turns out that bone formation ...

Oncology & Cancer

Scientists identify new target for wide array of cancers

Many types of human cancers exhibit changes in kinase and phosphatase balances. Drugs that inhibit kinase activity have shown success in the clinic as cancer therapeutics, but the phosphatases still remain a largely underexploited ...

Genetics

Discovery shows promise for treating Huntington's disease

Huntington's disease is a progressive and aggressively debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition. It is caused by a mutation in the gene that encodes the ...

Oncology & Cancer

Mystery about the cancer drug nelarabine solved after decades

Acute lymphoblastic leukemia (ALL) is the most common kind of cancer in children. T-ALL, a subtype that resembles T-lymphocytes, can be treated successfully with the drug nelarabine. The drug has not been successful, however, ...

Medical research

Self-healing bone cement developed

Materials scientists at the University of Jena have developed a bone replacement based on calcium phosphate cement and reinforced with carbon fibers. The fibers increase damage tolerance and ensure that cracks in the material ...

Oncology & Cancer

Study shows Nox4 protein may predict untreatable kidney cancer

A team of researchers from The University of Texas Health Science Center at San Antonio confirmed the role of a certain protein in the development of high-grade kidney cancer. The researchers also showed that a higher level ...

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Phosphate

A phosphate, an inorganic chemical, is a salt of phosphoric acid. In organic chemistry, a phosphate, or organophosphate, is an ester of phosphoric acid. Organic phosphates are important in biochemistry and biogeochemistry or ecology. Inorganic phosphates are mined to obtain phosphorus for use in agriculture and industry. At elevated temperatures in the solid state, phosphates can condense to form pyrophosphates.

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