Genetics

Discovery shows promise for treating Huntington's disease

Huntington's disease is a progressive and aggressively debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition. It is caused by a mutation in the gene that encodes the ...

Oncology & Cancer

FDA approves personalized therapy for metastatic bladder cancer

(HealthDay)—The first personalized treatment for patients with metastatic bladder cancer and susceptible fibroblast growth factor receptor (FGFR) genetic alterations was granted accelerated approval by the U.S. Food and ...

Cardiology

Researchers pinpoint new drug target for heart failure patients

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ...

Medical research

Cancer cells can reuse apparent 'dead end metabolites'

Researchers at Winship Cancer Institute of Emory University have discovered that an apparent "dead end metabolite" has a previously unknown function regulating cell growth. The finding could guide efforts to target cancer ...

Diseases, Conditions, Syndromes

Unique mechanism of action inhibiting paracellular phosphate absorption

Ardelyx, Inc. today announced that the novel mechanism of action for tenapanor for the treatment of hyperphosphatemia, or elevated serum phosphorus, has been published in the peer-reviewed journal Science Translational Medicine. ...

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