Diseases, Conditions, Syndromes

Unique mechanism of action inhibiting paracellular phosphate absorption

Ardelyx, Inc. today announced that the novel mechanism of action for tenapanor for the treatment of hyperphosphatemia, or elevated serum phosphorus, has been published in the peer-reviewed journal Science Translational Medicine. ...

Health

Vitamin D linked to mitochondrial oxidative function

(HealthDay)—For vitamin D deficient individuals, cholecalciferol therapy is associated with reduced phosphocreatine recovery half-time in skeletal muscle and with improvements in fatigue, according to a study presented ...

Diseases, Conditions, Syndromes

Pediatric kidney disease tied to abnormal carotid arteries

(HealthDay)—Ultrasound measurements of carotid intima-media thickness (cIMT) are significantly elevated among children with chronic kidney disease (CKD) compared with healthy controls, according to a study published online ...

Oncology & Cancer

Improved survival for patients with chronic blood diseases

(Medical Xpress) -- New research from Karolinska Institutet shows that the survival for patients with chronic myeloproliferative diseases has improved in recent decades. This is despite the fact that no targeted drugs have ...

Oncology & Cancer

Aurora-A hinders tumor-suppressor to allow chemotherapy resistance

A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists ...

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Phosphorus

Phosphorus (pronounced /ˈfɒsfərəs/) is the chemical element that has the symbol P and atomic number 15. A multivalent nonmetal of the nitrogen group, phosphorus is commonly found in inorganic phosphate rocks. Elemental phosphorus exists in two major forms - white phosphorus and red phosphorus. Although the term "phosphorescence", meaning glow after illumination, derives from phosphorus, glow of phosphorus originates from oxidation of the white (but not red) phosphorus and should be called chemiluminescence.

Due to its high reactivity, phosphorus is never found as a free element in nature on Earth. The first form of phosphorus to be discovered (white phosphorus, discovered in 1669) emits a faint glow upon exposure to oxygen — hence its name given from Greek mythology, Φωσφόρος meaning "light-bearer" (Latin Lucifer), referring to the "Morning Star", the planet Venus.

Phosphorus is a component of DNA, RNA, ATP, and also the phospholipids which form all cell membranes. It is thus an essential element for all living cells. The most important commercial use of phosphorus-based chemicals is the production of fertilizers.

Phosphorus compounds are also widely used in explosives, nerve agents, friction matches, fireworks, pesticides, toothpaste and detergents.

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