Medications

Repurposed cancer treatments could be potential Alzheimer's drugs

Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances. Research combining ...

Cardiology

Lowering the cost of heart cell therapies

Suffering from the number one cause of death, patients with heart disease are in desperate need of new therapies. However, these new therapies rely on research using heart cells, which are not easy to access. In response, ...

HIV & AIDS

Diabetes drug may be a new weapon against HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems ...

Oncology & Cancer

Feeding off fusion or the immortalization of tumor cells

Worldwide, cancer is the second leading cause of death—in 2018 alone, it claimed approximately 9.6 million lives, or one in six deaths. The development of cancer is incredibly complex and is controlled by an interplay of ...

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Phosphorylation

Phosphorylation is the addition of a phosphate (PO43-) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes.

Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).

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