A new study has identified novel mechanisms whereby T cells may be able to distinguish an emerging class of targets specifically increased on cancer cells.
Apr 13, 2017
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One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment—before symptoms of memory problems begin to surface. Whether it is ...
Jan 31, 2017
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In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming ...
Sep 22, 2016
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Scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have discovered that modifications to a protein called RUNX3 may promote cancer progression. The results ...
Jul 15, 2016
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Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a ...
Jul 12, 2016
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Cancer cells commonly rely on glycolysis, the type of metabolism that does not use oxygen to generate their energy however, researchers from Queen Mary University of London's Barts Cancer Institute and the Spanish National ...
Sep 10, 2015
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A protein known to play a role in transporting the molecular contents of normal cells into and out of various intracellular compartments can also turn such cells cancerous by stimulating a key growth-control pathway.
Sep 3, 2015
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In a new study by Sanford Burnham Prebys Medical Discovery Institute (SBP), researchers have identified a novel kinase cascade that regulates mTORC1, a protein complex implicated in the control of cancer cell growth in response ...
Aug 14, 2015
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Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.
Jul 8, 2015
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Mitochondrial diseases are highly heterogeneous disorders characterized by faulty oxidative phosphorylation. OPA1 is a protein of the inner mitochondrial membrane, which shapes mitochondrial cristae, the structures where ...
Jun 5, 2015
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