Worldwide, cancer is the second leading cause of death—in 2018 alone, it claimed approximately 9.6 million lives, or one in six deaths. The development of cancer is incredibly complex and is controlled by an interplay of ...
Sep 11, 2020
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In the first study to comprehensively track how different types of brain cells respond to the mutation that causes Huntington's disease (HD), MIT neuroscientists found that a significant cause of death for an especially afflicted ...
Jul 17, 2020
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Researchers at the University of Liverpool have made a major breakthrough in the field of cell signalling.
Nov 4, 2019
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A molecular process involved in the action of anti-leukemia drugs has been discovered at Université de Montréal's Institute for Research in Immunology and Cancer (IRIC). While calling into question a central tenet of oncology, ...
Jul 9, 2019
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Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the ...
Jun 11, 2019
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When considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unlike some of its more sedate cytokine cousins which studiously direct the immune response ...
Jun 3, 2019
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Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells. When hematopoietic stem cells mutate in specific ways, the ...
Sep 12, 2018
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Chronic active Epstein-Barr virus infection (CAEBV) is an EBV-positive T- or NK-cell neoplasm accompanied by sustained systemic inflammation. Many studies have attempted to understand the case of CAEBV; none have provided ...
Aug 21, 2018
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Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth ...
Mar 29, 2018
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A new study conducted by researchers at The Wistar Institute revealed how a key protein residing in the endoplasmic reticulum (ER) helps cells respond to stress. This process is especially important for B cells to respond ...
Mar 6, 2018
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