A series of papers published recently by two teams of vision researchers at the University at Buffalo and the University of Alabama at Birmingham (UAB) is revealing important new information about the possible cause of a ...
Jun 24, 2020
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Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, expected to see retinal degeneration and retinal thinning. As reported in the journal Cells, they surprisingly found none, ...
Jun 11, 2020
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Multi-disciplinary work led by researchers from Trinity has pinpointed a potential new therapeutic target for treating retinal degeneration. The researchers have discovered that a protein (SARM1) involved in neuronal cell ...
Apr 20, 2020
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Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into ...
Apr 15, 2020
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Creating an effective gene therapy for inherited diseases requires three key steps. First, scientists must identify and characterize the disease. Second, they must find the gene responsible. And finally, they must find a ...
Oct 4, 2019
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Nearly two decades ago, a gene therapy restored vision to Lancelot, a Briard dog who was born with a blinding disease. This ushered in a period of hope and progress for the field of gene therapy aimed at curing blindness, ...
Sep 10, 2019
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Photoreceptor cells in our eyes can adjust to both weak and strong light levels, but we still don't know exactly how they do it. Emeritus Professor Fumio Hayashi of Kobe University and his colleagues revealed that the photoreceptor ...
Jun 24, 2019
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Advances in preclinical research are now being translated into innovative clinical solutions for blindness, a review published in the 10th Anniversary Series of Science Translational Medicine reports.
Jun 5, 2019
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National Institutes of Health scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, ...
Mar 27, 2019
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It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice ...
Mar 15, 2019
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