Research suggests probiotics plus vitamin D supplements may benefit people with schizophrenia
Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.
Apr 10, 2024
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Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.
Apr 10, 2024
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Treatment with ticagrelor alone results in a lower rate of clinically relevant bleeding compared with ticagrelor and aspirin among patients with an acute coronary syndrome who had percutaneous coronary intervention and remained ...
Apr 13, 2024
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A drug approved to treat pulmonary arterial hypertension may be effective at managing hypertension and end-organ damage in patients with sickle cell disease, according to a new study published in Lancet Haematology.
Apr 11, 2024
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A single low dose of esketamine after childbirth reduces depressive episodes at 42 days postpartum among mothers with prenatal depression, according to a study published online April 10 in The BMJ.
Apr 20, 2024
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One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment ...
Apr 8, 2024
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For patients with gastric/gastroesophageal junction (G/GEJ) adenocarcinoma, cadonilimab plus chemotherapy is associated with improved overall survival and progression-free survival, according to a study presented at the annual ...
Apr 8, 2024
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A placebo is a sham medical intervention. In one common placebo procedure, a patient is given an inert sugar pill, told that it may improve his/her condition, but not told that it is in fact inert. Such an intervention may cause the patient to believe the treatment will change his/her condition; and this belief does indeed sometimes have a therapeutic effect, causing the patient's condition to improve. This phenomenon is known as the placebo effect.
Placebos are widely used in medicine, and the placebo effect is a pervasive phenomenon; in fact, it is part of the response to any active medication. However, the deceptive nature of the placebo creates tension between the Hippocratic Oath and the honesty of the doctor-patient relationship. The placebo effect points to the importance of perception and the brain's role in physical health.
Since the publication of Henry K. Beecher's The Powerful Placebo in 1955 the phenomenon has been considered to have clinically important effects. This view was notably challenged when in 2001 a systematic review of clinical trials concluded that there was no evidence of clinically important effects, except perhaps in the treatment of pain and continuous subjective outcomes. The article received a flurry of criticism, but the authors later published a Cochrane review with similar conclusions. Most studies have attributed the difference from baseline till the end of the trial to a placebo effect, but the reviewers examined studies which had both placebo and untreated groups in order to distinguish the placebo effect from the natural progression of the disease.
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