Scientists at the Stanford University School of Medicine have shown how a protein fragment known as beta-amyloid, strongly implicated in Alzheimer's disease, begins destroying synapses before it clumps into plaques that lead ...
Sep 19, 2013
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In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels—called vascular endothelial cells—from human induced pluripotent stem cells (iPSCs), revealing ...
Aug 22, 2013
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(Medical Xpress) -- Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a novel biomimetic strategy that delivers life-saving nanotherapeutics directly to obstructed ...
Jul 5, 2012
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A one-dose method for delivering gene therapy into an arterial wall effectively protects the artery from developing atherosclerosis despite ongoing high blood cholesterol. The promising results, published July 19 in the journal ...
Jul 19, 2011
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The buildup of fat in the liver, known as non-alcoholic fatty liver disease, or NAFLD for short, is linked to a heightened risk of heart failure over the next decade, finds a pooled data analysis of the available research, ...
Jul 25, 2022
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Amyloid plaque formation directly causes brain tissue loss in animals, but a drug called lithium reduces the life-shortening effects of this loss, shows a study published today in eLife.
Mar 31, 2020
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Atherosclerosis is the slow and progressive narrowing of arteries due to plaque formation. The atherosclerotic plaque forms by local proliferation of leukocytes and vascular smooth muscle cells (VSMCs) in the vessel wall ...
Jul 15, 2019
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It may be too late to stop Alzheimer's in people who already have some mental decline. But what if a treatment could target the very earliest brain changes while memory and thinking skills are still intact, in hope of preventing ...
Oct 2, 2018
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Considering what little progress has been made finding drugs to treat Alzheimer's disease, Maikel Rheinstädter decided to come at the problem from a totally different angle—perhaps the solution lay not with the peptide ...
Sep 11, 2018
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A breakthrough by Wits scientists could see patients with Alzheimer's use a nasal spray to slow down the progression of the disease, the main cause of dementia.
Sep 7, 2018
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