Medical research

When the body's B cell training grounds stay open after hours

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities. ...

Immunology

Tracking the pathway to immunity, one cell at a time

Vaccines work their magic by effectively creating immune cells that are long lived, often for over decades. These immune cells create both a protective barrier that can prevent or minimize re-infection and a memory that allows ...

Oncology & Cancer

Researchers uncover new target to stop cancer growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes—tiny, membrane-bound packages containing proteins and RNAs that stimulate ...

Immunology

Why protecting the brain against infection takes guts

The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally ...

Medical research

Popular diabetes drugs' cardiovascular side effects explained

Drugs known as thiazolidinediones, or TZDs for short, are widely used in diabetes treatment, but they come with a downside. The drugs have effects on the kidneys that lead to fluid retention as the volume of plasma in the ...

Medical research

Bioelectric signals in breast cancer metastasis studied

Metastasis accounts for approximately 90 percent of mortality in breast cancer patients. During the last few decades, there has been significant progress in understanding genetic, molecular and signaling mechanisms underpinning ...

page 5 from 27