PLoS Biology is an American scientific journal covering the full spectrum of the biological sciences that began operation on October 13, 2003.
It was the first journal of the Public Library of Science (PLoS) a non-profit organization which releases scientific content under open access terms. All content in PLoS Biology is published under the Creative Commons "by-attribution" license, abbreviated CCAL. To fund the journal, the publication's business model requires that, in most cases, authors will pay publication costs.
In addition to research articles, PLoS Biology publishes online e-letters in which the readers provide their comments to the articles.
The impact factor of PLoS Biology for 2007, as calculated by the Institute for Scientific Information (ISI), was 13.5. To put this in context, it is the highest-ranked of all journals in the ISI category 'Biology'.
The current Academic Editor in Chief is Jonathan Eisen from U. C. Davis.