Genetics

Artificial RNA editing with ADAR for gene therapy

Many of the diseases caused by point mutations have no established therapeutic approaches. Prof. Tsukahara and colleagues (Japan Advanced Institute of Science and Technology) are studying a therapeutic method using artificial ...

Neuroscience

How nerves may lose their insulation

Charcot-Marie-Tooth (CMT) disease is the most common inherited disorder of the peripheral nerves in humans, affecting 1 in every 2,500 people. There is no cure for the disease, which causes severe disability due to disruptions ...

Oncology & Cancer

No tumor is an island

For decades tumors have been viewed as 'other'—malignant, unruly growths that are distinctly separate from the ordered physiological system within which they live. This view has shaped our approach to treat cancer: cut ...

Oncology & Cancer

Stopping cancer from recruiting immune system double agents

Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread). A ...

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