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COVID-19 testing of children before anesthesia saves PPE

Universal COVID-19 testing of children who are having procedures requiring anesthesia promotes efficient use of personal protective equipment (PPE), according to research being presented at the ANESTHESIOLOGY 2020 annual ...

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What are the new types of tests for COVID-19?

The list of testing options for COVID-19 keeps growing, and the different types of tests are not always explained. Tests range from ones that use samples sent into testing labs to ones that could be performed at a health ...

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The road to COVID-19 testing: The role of a Canadian biotech pioneer

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Polymerase

A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a cluster of other enzymes and proteins, they take nucleotides from solvent, and catalyse the synthesis of a polynucleotide sequence against a nucleotide template strand using base-pairing interactions.

It is an accident of history that the enzymes responsible for the catalytic production of other biopolymers are not also referred to as polymerases.

One particular polymerase, from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is of vital commercial importance due to its use in the polymerase chain reaction, a widely used technique of molecular biology.

Other well-known polymerases include:

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