Oncology & Cancer

LIM domain only 1: One gene, many roles in cancer

Humans have long been plagued by a myriad of deadly cancers. Parallelly, they attempted different permutations and combinations of treatments to cure the disease. Attempts involving biomolecular targets have come to the fore ...

Oncology & Cancer

Study of NCOA3 yields novel findings of melanoma progression

For the first time, activation of nuclear receptor coactivator 3 (NCOA3) has been shown to promote the development of melanoma through regulation of ultraviolet radiation (UVR) sensitivity, cell cycle progression and circumvention ...

Genetics

Induced pluripotent stem cells reveal causes of disease

Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex, rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory ...

Diseases, Conditions, Syndromes

Scientists demonstrate how genetic variations cause eczema

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, ...

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