Genetics

Gene variant increases fatty liver risk and fibrosis progression

New research confirms that a variant on the patatin-like phospholipase-3 (PNPLA3) gene increases risk of steatosis and fibrosis progression in patients with chronic hepatitis C virus (HCV). The PNPLA3 single nucleotide polymorphism ...

Genetics

What role do genome variations play in tuberculosis?

Tuberculosis is caused by Mycobacterium tuberculosis. In 2016, this was the most common causative pathogen for death by infectious diseases. Therefore, investigating the biology of infection and disease development is important ...

Medical research

Genetic variant discovery to help asthma sufferers

Research from the University of Liverpool, published today in Lancet Respiratory Medicine, identifies a genetic variant that could improve the safety and effectiveness of corticosteroids, drugs that are used to treat a range ...

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