Oncology & Cancer

Scientists kill cancer cells by 'shutting the door' to the nucleus

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes—large channels that control the flow of materials in and out of the cell nucleus—shrank ...

Medical research

A bacterial toxin turning cells into swiss cheese

Although the innate immune system is the front line of defense against microbial infections, the complex mechanisms of innate immunity are incompletely understood. In a new study, researchers from Kanazawa University synthesized ...

Medical research

Scars: Gone with the foam

A scar on the elbow that is strained with every movement, or a foot, on which a wound simply does not want to close—poorly healing injuries are a common cause of health restrictions. And although millions of people are ...

Immunology

Researchers stop cell suicide that worsens sepsis, arthritis

Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis.

Neuroscience

Research discovers new channel-gating mechanism

Computational biophysicists are not used to making discoveries, says Jianhan Chen at the University of Massachusetts Amherst, so when he and colleagues cracked the secret of how cells regulate Big Potassium (BK) channels, ...

Oncology & Cancer

Nuclear gatekeeper could block undruggable prostate cancer targets

Certain molecular drivers of cancer growth are "undruggable—it's been nearly impossible to develop chemicals that would block their action and prevent cancer growth. Many of these molecules function by passing cancer-promoting ...

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Pore

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