Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes. To date, no treatment options exist for this class of disorders. MECP2 duplication syndrome (MDS) is ...
Mar 04, 2021
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A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes Middle East respiratory syndrome (MERS) found that they were well tolerated and generally ...
Feb 23, 2021
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Can stem cells alleviate lymphedema, a chronic debilitating condition affecting up to one in three women treated for breast cancer? Results of a phase I clinical trial released today in STEM CELLS Translational Medicine (SCTM) ...
Feb 18, 2021
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Tumor cells are able to avoid the attack of the immune system through several mechanisms. For instance, they can secrete factors that turn macrophages, cells in the immune system, into dual-action agents that contribute to ...
Feb 12, 2021
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Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success story. Smallpox vaccination led to the disease's eradication in the twentieth century. Until very recently, smallpox vaccine ...
Jan 27, 2021
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US biotechnology firm Moderna on Monday said lab studies showed its COVID-19 vaccine remains effective against variants of the coronavirus first identified in the United Kingdom and South Africa.
Jan 25, 2021
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Chimeric Antigen Receptor T-cell therapy—CAR T—has revolutionized leukemia treatment. Unfortunately, the therapy has not been effective for treating solid tumors including childhood cancers such as neuroblastoma. Preclinical ...
Jan 22, 2021
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Just a few millimeters thick, articular cartilage plays a crucial role in our musculoskeletal system, since it is responsible for smooth (in the truest sense of the word) movement. However, the downside of its particular ...
Jan 20, 2021
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Scientists at The Wistar Institute characterized an inhibitor that targets acetate metabolism in cancer cells. Cancer cells use acetate metabolism to support tumor growth in conditions of low nutrient and oxygen availability. ...
Jan 07, 2021
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Despite the progress made in managing asthma and chronic obstructive pulmonary disease (COPD), poorly controlled symptoms for both respiratory diseases can lead to severe shortness of breath, hospitalizations or even death.
Jan 04, 2021
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