Alzheimer's disease & dementia

New drug targets early instigator of Alzheimer's disease

Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...

Alzheimer's disease & dementia

Modified protein can prevent Alzheimer's disease in mice

The amyloid precursor protein has always been vilified as a major cause of Alzheimer's disease. One of its fragments, the amyloid-beta peptide, can break off and accumulate in the brain, giving rise to the puffy white globs ...

Alzheimer's disease & dementia

New Alzheimer therapy passes another important test

The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active ...

Alzheimer's disease & dementia

Scientists propose new theory on Alzheimer's, amyloid connection

Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops this disease, which causes problems with ...

Neuroscience

Defining the brain mosaic in fruit flies and humans

Similar to a mosaic floor where different patterned tiles come together to make a composite and holistic image, our brains consist of billions of unique neurons that connect and generate coordinated brain activity. Unlike ...

Alzheimer's disease & dementia

Mutation discovered to protect against Alzheimer's disease in mice

Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific ...

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