An international team of researchers has discovered a new binding partner for amyloid precursor protein (APP)—a neurotransmitter called GABABR1a. In their paper published in the journal Science, the group describes their ...
Alzheimer's-affected brains are riddled with amyloid plaques, protein aggregates consisting mainly of amyloid-β. However, amyloid-β is a fragment produced from a precursor protein whose normal function has remained enigmatic ...
Jan 11, 2019
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(HealthDay)—Seven in 10 people with Down syndrome show evidence of dementia when they die, new research from Britain reveals.
Nov 19, 2018
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Similar to a mosaic floor where different patterned tiles come together to make a composite and holistic image, our brains consist of billions of unique neurons that connect and generate coordinated brain activity. Unlike ...
Jun 27, 2018
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Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific ...
May 16, 2018
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A protein involved in Alzheimer's disease (AD) may be a promising target for treating neurological disorders in human immunodeficiency virus (HIV) patients, suggests a study published in JNeurosci of rat neurons and brain ...
Apr 09, 2018
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A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's ...
Feb 14, 2018
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Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check. The study, published in Nature Communications, ...
Nov 14, 2017
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Red blood cells are formed in the bone marrow from haematopoietic stem cells via a complex process known as erythropoiesis. Towards the end of this process, immature red blood cells also known as reticulocytes (multi-lobular ...
Nov 02, 2017
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Scientists at the Massachusetts General Hospital (MGH), in collaboration with colleagues at the University California, San Diego (UCSD), have characterized a new class of drugs as potential therapeutics for Alzheimer's disease ...
Oct 18, 2017
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