Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer's disease by modulating, rather than inhibiting, a key enzyme ...
Mar 02, 2021
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Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons ...
Feb 19, 2021
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Alzheimer's disease is the leading cause of dementia worldwide and a major cause of disability. Now, researchers at Osaka University and Hokkaido University have shown that repeated precipitation-dissolution events of salt ...
Jul 27, 2020
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A gene has been discovered that can naturally suppress the signs of Alzheimer's Disease in human brain cells, in research led by Queen Mary University of London. The scientists have also developed a new rapid drug-screening ...
Jul 09, 2020
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A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer's disease. As published ...
Feb 03, 2020
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Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...
Aug 14, 2019
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The amyloid precursor protein has always been vilified as a major cause of Alzheimer's disease. One of its fragments, the amyloid-beta peptide, can break off and accumulate in the brain, giving rise to the puffy white globs ...
Jun 14, 2019
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Apolipoproten E (apoeE) is a major genetic risk factor for the development of Alzheimer's disease, yet the protein tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease.
Jun 12, 2019
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The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active ...
May 13, 2019
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Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops this disease, which causes problems with ...
Apr 23, 2019
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