New research led by Harvard Medical School and Brigham and Women's Hospital has unmasked hundreds of cancer-driving genes and revealed that different tissue types have shockingly variable sensitivities to those genes.
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The fact that asbestos causes cancer has been largely undisputed for nearly 50 years. Now, researchers supported by the Swiss National Science Foundation (SNSF) have discovered why the fibres cause such damage to the body. ...
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The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer. EGFR, present on the cell membrane, ...
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In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury. After a heart attack, there is a dramatic loss of these heart muscle cells and those that survive ...
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(HealthDay)—About one-quarter of skin biopsies are diagnosed as melanocytic proliferation, according to a study published online Nov. 1 in JAMA Dermatology.
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In the brains of Alzheimer's patients, many of the genes required to form new memories are shut down by a genetic blockade, contributing to the cognitive decline seen in those patients.
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A subspecies of the bacterium Streptococcus gallolyticus appears to actively promote the development of colorectal cancer, according to new research published in PLOS Pathogens.
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Type XVII collagen (COL17) is found to regulate the proliferation of epidermal cells and therefore the thickness of juvenile and aged skin, suggesting COL17 can potentially be used for future anti-aging strategies.
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The mammalian immune system consists of millions of individual cells that are produced daily from precursor cells in the bone marrow. During their development, immune cells undergo a rapid expansion, which is interrupted ...
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Polycomb group (PcG) proteins comprise the polycomb complexes PRC1 and PRC2 that regulate gene expression levels through histone modification. Although PRC1 and PRC2 have important roles in cancer stem cells, their functions ...
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