Cardiology

The immune system promotes spontaneous heart regeneration

In adult mammal hearts, cardiomyoctyes do not proliferate following damage such as that caused by myocardial infarction. However, in some mammals, cardiomyocyte proliferation occurs. "Neonatal cardiomyocytes proliferate, ...

Oncology & Cancer

Scientists solve major cancer protein conundrum

Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell ...

Medical research

Cellular senescence prevented by the SETD8 enzyme

An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and ...

Oncology & Cancer

New protein discovered in aging and cancer

A protein has been found to have a previously unknown role in the ageing of cells, according to an early study by Queen Mary University of London (QMUL). The researchers hope that the findings could one day lead to new treatments ...

Oncology & Cancer

Ki67 may help avoid sentinel lymph node biopsy in some patients

Breast cancer patients over 50 years old could be spared invasive procedures by use of stratification based on tumour size and molecular characteristics, including Ki67. The cell proliferation index Ki67 is significantly ...

Oncology & Cancer

A new tumor suppressor gene for breast cancer in mice

Researchers at Tokyo Institute of Technology revealed a role for an X-linked protein kinase Nrk in terminating the proliferation of mammary epithelial cells during pregnancy and thereby preventing breast tumorigenesis in ...

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