Diseases, Conditions, Syndromes

What should a successful SARS-CoV-2 vaccine do?

A lot has been written recently about the merits of different potential vaccines for SARS-CoV-2. "Merit" is generally assumed to mean that the vaccine will make us immune. But what, exactly, is immunity, and how would we ...

Medical research

3-D images show how sperm binds to the egg surface

Researchers at Karolinska Institutet in Sweden have obtained the first 3D snapshots of a sperm protein attached to a complementary egg coat protein at the beginning of fertilisation. The study, which reveals a common egg ...

Diseases, Conditions, Syndromes

Protein critical to early stages of cellular HIV infection identified

When a virus enters a cell, one of the first steps in the process of infecting that cell is removal of the protein coat that surrounds the virus's genetic material. The virus can then produce DNA from its own genes and insert ...

HIV & AIDS

A 'public' target for HIV

Individuals produce unique sets of antibodies in response to HIV infection. That diversity—and the ability of the human immunodeficiency virus to rapidly change its protein coat to avoid detection—has stymied efforts ...

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