Oncology & Cancer

Biomarker predicts resistance to immunotherapies in melanoma

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system ...

HIV & AIDS

Study identifies how stealthy HIV evades drugs and immunity

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health ...

Medical research

Understanding oral bacteria to help fight periodontal disease

Using the extremely brilliant light of the Canadian Light Source at the University of Saskatchewan, researchers from Wilfrid Laurier University have advanced our understanding of how a specific group of bacteria in the human ...

Genetics

Killer T vs. memory: DNA isn't destiny for T cells

Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical. The researchers ...

Immunology

Mitochondrial respiratory chain sustains inflammation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain—a series of protein complexes essential for a cellular respiration and energy production—is necessary for the activation ...

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