Neuroscience

Probing the pathology of impaired cognition

Neurofilament light (NFL) is a support protein within large axons in the brain's white matter that supports nerve signal transmission. When axons are injured, increased NFL concentrations are found in the cerebrospinal fluid ...

Parkinson's & Movement disorders

Parkinson's disease: New insights into a traveling protein

In Parkinson's disease, the protein "alpha-synuclein" aggregates within neurons of patients and appears to propagate across interconnected areas of the brain. How this happens remains largely unknown. It has been proposed ...

Medical research

New insights into functionality of cystic fibrosis protein

CFTR is an important protein that, when mutated, causes the life-threatening genetic disease cystic fibrosis. A study in The Journal of General Physiology (JGP) details how an accidental discovery has provided new understanding ...