New software screens billions of compounds in search of new medicines
As many as 90 percent of promising drug candidates fail before or during human clinical trials, falling into the so-called "valley of death."
Mar 16, 2020
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As many as 90 percent of promising drug candidates fail before or during human clinical trials, falling into the so-called "valley of death."
Mar 16, 2020
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Researchers in the United States have identified a molecular network that comprises many of the genes previously shown to contribute to autism spectrum disorders. The findings provide a map of some of the crucial protein ...
Dec 30, 2014
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A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes. The ...
Nov 12, 2020
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Many roads can lead to the same place, often crossing over one another and sometimes passing the same landmarks.
Jun 8, 2011
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Scientists have long known that proteins can form harmful clusters in neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). But a new study by Penn State researchers ...
Jun 2, 2022
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Doctors may someday be able to use bodily fluids to noninvasively detect breast cancer in patients earlier than is possible now.
Mar 16, 2024
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National Institutes of Health researchers have reversed behaviors in mice resembling two of the three core symptoms of autism spectrum disorders (ASD). An experimental compound, called GRN-529, increased social interactions ...
Apr 25, 2012
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In a study published in Nature Communications, a team led by Krembil Brain Institute at UHN Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, has identified ...
Apr 19, 2023
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UNC-Chapel Hill researchers have, for the first time, determined the high-resolution structure of a key DNA-sensing protein in the innate immune system called cGAS while it is bound to the nucleosome—the all-important unit ...
Sep 10, 2020
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A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).
Aug 17, 2020
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