Oncology & Cancer

New results on the function of the tumor suppressor HERC protein

The RAF protein could be a therapeutical target to treat tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine ...

Medical research

Team explores pathway to open up blood cancer treatments

Reversing runaway inflammation in the bone marrow could lead to major breakthroughs in treatments for some blood cancers, according to a new publication by scientists at Hackensack Meridian Health's Center for Discovery and ...

Cardiology

A kinase identified as possible target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies. Failing human hearts showed reduced amounts of this kinase, and preclinical ...

Medical research

Putting the squeeze on red blood cells

For the first time, researchers at the University of Bristol's Blood and Transplant Research Unit, and the French National Institute for Blood Transfusion, have captured the moment a red blood cell is "squeezed" while recording ...

Oncology & Cancer

Scientists develop possible strategy for cancer drug resistance

Scientists from the National Institutes of Health and Cincinnati Children's Hospital Medical Center have devised a potential treatment against a common type of leukemia that could have implications for many other types of ...

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Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Protein kinases are also found in bacteria and plants. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction.

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