Immunology

Research discoveries uncover secrets of immune system

A series of discoveries made by scientists at the University of Dundee is helping to uncover the secrets of how chronic inflammatory and autoimmune diseases such as Lupus and rheumatoid arthritis are caused and could lead ...

Neuroscience

Balancing mitochondrial dynamics in Alzheimer's disease

(Medical Xpress)—Many diseases are multifactorial and can not be understood by simple molecular associations alone. Alzheimer's disease (AD)is associated with toxic transformations in two classes of protein,amyloid beta ...

Neuroscience

Controlling mood through the motions of mitochondria

(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined into narrow neuritic ...

Medical research

Giant raft of data to help us understand disease

Scientists at the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen have used a new method to assemble a massive catalogue of data on proteins. This gives them unprecedented insight into ...

Parkinson's & Movement disorders

Molecular 'on-off' switch for Parkinson's disease discovered

(Medical Xpress) -- Scientists at the Medical Research Council (MRC) Protein Phosphorylation Unit at the University of Dundee have discovered a new molecular switch that acts to protect the brain from developing Parkinson's ...

Oncology & Cancer

Researchers identify drivers of sarcoma growth and survival

To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or ...

Diabetes

Metal binding important for metformin action

(HealthDay) -- The ability of metformin to bind mitochondrial copper may be essential to its mechanism of action, according to a study published online April 9 in Diabetes.

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