Like a bank robber on the lam, Gpr182 had assumed a variety of identities over several decades: G10D, HrhAMR, Gamrh, 7TMR, ADMR. Unable to put a finger on what exactly the gene does, scientists largely left it alone. The ...
Jan 20, 2017
0
58
Saying that the sense of taste is complicated is an understatement, that it is little understood, even more so. Exactly how cells transmit taste information to the brain for three out of the five primary taste types was pretty ...
Mar 6, 2013
0
0
Working with mice, Johns Hopkins researchers report they have found previously known skin itch receptors in the airways that appear to contribute to bronchoconstriction and airway hypersensitivity, hallmarks of asthma and ...
Mar 9, 2018
0
41
Activation of a receptor with no known function in the brain reduces excessive alcohol use and the pain of withdrawal, according to preclinical research in male rats. The study, published in eNeuro, suggests a new approach ...
Jun 25, 2018
0
2
Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Oct 10, 2012
0
0
G protein-coupled receptors (GPCRs) are popular drug targets, accounting for about one-third of approved drugs and many hundreds of drugs currently in development. They act as molecular switches that transduce extracellular ...
Jul 26, 2011
0
0
Canadian researchers, working in partnership with Brazilian colleagues, have developed 13 bioluminescence sensors for use in testing the effectiveness of new medical drugs in the laboratory. The study, published in the journal ...
Mar 4, 2019
0
27
There was a time when Thomas Huber, a molecular biologist at The Rockefeller University, was drinking about 36 ounces of diet cola a day. More than a year ago, Huber, a research assistant professor in Thomas P. Sakmar's Laboratory ...
Jun 3, 2016
0
45
Biologists from Bochum and Bonn have detected a cannabinoid receptor in spermatozoa. Endogenous cannabinoids that occur in both the male and the female genital tract activate the spermatozoa: they trigger the so-called acrosome ...
Aug 30, 2016
0
0
In recent years, a growing body of evidence has linked inflammation to the development of insulin resistance. In insulin resistance, the hormone insulin is less effective in promoting glucose uptake from the bloodstream into ...
Jun 1, 2012
0
0
