Oncology & Cancer

New strategy to reduce cancer drug's cardiotoxic effects

Doxorubicin (Doxo) is a widely used chemotherapeutic drug for cancer, though it can have toxic effects on the heart. A recent animal study published in The FASEB Journal investigated whether the cardioregulatory protein chromogranin ...

Psychology & Psychiatry

Menstrual cycle phase influences cocaine craving

Menstrual cycle may influence addiction risk in women, according to a new study in Biological Psychiatry by researchers at the National Institute on Drug Abuse and University of Maryland School of Medicine. In female rats, ...

Health

Binge drinking during youth may impact future offspring

A rat model found preconception binge drinking may have negative consequences on future offspring's growth, social interactions and pubertal development, according to a new study published in the Endocrine Society's Journal ...

Neuroscience

Stress regulates self-harm in rats

A stress hormone modulates compulsive biting in a rat model of self-injurious behavior (SIB), according to new research published in JNeurosci. Manipulating the activity of the brain circuitry underlying SIB could create ...

Alzheimer's disease & dementia

New tools could uncover important answers for Alzheimer's researchers

Alzheimer's disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer's Association. Characterized by a buildup of plaque in the brain, few animal ...

Diseases, Conditions, Syndromes

New compound stops progressive kidney disease in its tracks

Progressive kidney diseases, whether caused by obesity, hypertension, diabetes, or rare genetic mutations, often have the same outcome: The cells responsible for filtering the blood are destroyed. Reporting today in Science, ...

Alzheimer's disease & dementia

Saving neurons may offer new approach for treating Alzheimer's disease

Treatment with a neuroprotective compound that saves brain cells from dying also prevents the development of depression-like behavior and the later onset of memory and learning problems in a rat model of Alzheimer's disease. ...

Cardiology

Why do we develop high blood pressure?

Abnormally high blood pressure, or hypertension, may be related to changes in brain activity and blood flow early in life. That's according to a study conducted on a rat model of high blood pressure, published in Experimental ...

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