Neuroscience

The discovery of a 'negative regulator' in the brain

The brain has an uncanny ability to enhance or reduce communication between brain cells. Whether or not communication is fast or slow changes the brain's overall function. Understanding how these cells communicate within ...

Immunology

How immune cells activate the killer mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign—so-called antigens—bind to the ...

Oncology & Cancer

How breast cancer cells sneak past local immune defenses

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body's immune system. That key player provides ...

Oncology & Cancer

New independent prognostic indicator in gastric cancer

Despite many developments in the diagnosis and treatment of gastric cancer, it continues to be an important public health problem. Therefore, besides classical methods, new biomolecules are needed to facilitate the prediction ...

Oncology & Cancer

Improved cancer immunotherapies require radical CAR overhaul

CAR-T cell therapy is a new and revolutionary weapon against cancer: T cells are isolated from the patient's blood for genetic modification and then infused back into the patient to attack cancer cells. Researchers from the ...

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