Alzheimer's disease & dementia

Alzheimer's drug may stop disease if used before symptoms develop

About 50 percent of people who reach the age of 85 will develop Alzheimer's disease. Most will die within about five years of exhibiting the hallmark symptoms of the disease – severe memory loss and a precipitous decline ...

Medications

Pain relief at a lower opioid dose

A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways—one that has previously been linked to how the brain senses "itch"—may improve pain relief when combined ...

Neuroscience

New insights into nicotine's effect on reward pathways

Northwestern scientists have discovered new mechanisms used by nicotine to manipulate the brain's reward pathway—findings which could inform the development of future anti-addiction therapies.

Medical research

Research explains link between exercise and appetite loss

Ever wonder why intense exercise temporarily curbs your appetite? In research described in today's issue of PLOS Biology, Albert Einstein College of Medicine researchers reveal that the answer is all in your head—more specifically, ...

Neuroscience

Scientists chart how brain signals connect to neurons

Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic ...

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