One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.
Apr 16, 2020
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A commonly expressed protein in skin—periostin—can directly activate itch-associated neurons in the skin, according to new research from North Carolina State University. The researchers found that blocking periostin receptors ...
Apr 7, 2020
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In hopes of developing a possible treatment for COVID-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses' ability to enter human cells. The potential drug is a short protein ...
Mar 30, 2020
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Glutamate receptors in the brain called AMPARs are critical for synaptic plasticity, learning and memory. Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, ...
Dec 9, 2019
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Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new ...
Nov 27, 2019
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In a recent study using mice, lab-grown human retinal cells and patient samples, Johns Hopkins Medicine scientists say they found evidence of a new pathway that may contribute to degeneration of the light sensitive tissue ...
Nov 27, 2019
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Scientists at Stanford and UC-San Francisco have developed an experimental drug that targets a currently untreatable type of lung cancer responsible for generating roughly 500,000 newly diagnosed cases worldwide each year.
Nov 7, 2019
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Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve ...
Sep 16, 2019
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A study led by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Communications proposes chaperone protein Hps70 as an attractive therapeutic target for the treatment of Kennedy's ...
Aug 8, 2019
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Researchers have long known that dozens of inherited diseases, called toxic proteinopathies, are caused by the build-up of specific misfolded proteins in cells. But, the molecular mechanisms responsible for this accumulation ...
Jul 25, 2019
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