Medical research

'Spleen-on-a-chip' yields insight into sickle cell disease

Every day, billions of red blood cells pass through the spleen, an organ that is responsible for filtering out old or damaged blood cells. This task is made more difficult when the blood cells are misshapen, as they are in ...

Oncology & Cancer

How a leukemia hijacks the genes needed by blood stem cells

As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...

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