Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.
Feb 6, 2024
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Professor Yi Sun's team at the Zhejiang University report a functional compensatory effect between the Ube2m-Rbx1 and Ube2f-Sag axes of the neddylation–Cullin-RING ligases (CRLs) system in Treg cells, using conditional ...
Dec 22, 2023
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A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, ...
Dec 6, 2023
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434
A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders ...
Nov 15, 2023
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5
The immune system is fast when it comes to fighting viruses, bacteria and other pathogens. But it also has to know when not to attack—for example, harmless substances such as pollen or house dust, which otherwise trigger ...
Oct 30, 2023
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The human gut—or gastrointestinal system—where food is broken down into nutrients for the body, is an ecosystem that harbors thousands of bacteria species. While some microorganisms are harmful, many are beneficial and ...
Sep 29, 2023
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How do our muscles respond at the molecular level to exercise? Researchers at Helmholtz Munich and the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have unraveled the cellular basis and signaling pathways ...
Sep 20, 2023
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Regulatory T cells—work horses of the body's immune system—may also stabilize mood, according to a study. Forkhead box P3 (Foxp3) is a transcription factor that controls the production of regulatory T cells (Tregs).
Aug 23, 2023
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146
According to the federal government's National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide—with almost a third in the United States—are living with multiple sclerosis (MS), a disabling ...
Jun 2, 2023
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A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP). ...
Apr 7, 2023
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