Medical research

Discovery suppresses progression of kidney fibrosis

Webster Santos is determined to find a way to halt kidney fibrosis, a condition caused by persistent inflammation and assault to the kidney. The disorder leads to kidney disease, itself a pathway to kidney failure, also known ...

Diseases, Conditions, Syndromes

Still an unmet need: New therapeutic targets in Alport syndrome

Alport syndrome (AS) is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure. Depending on the mutated gene and the pattern of inheritance, there are three types ...

Diseases, Conditions, Syndromes

Scientists report new approach to reduce or prevent renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. Using genetically altered mice, researchers from Duke University investigated ...

Oncology & Cancer

Diagnostic mutations ID'd in chronic kidney disease patients

(HealthDay)—About one-quarter of adults with chronic kidney disease (CKD) of unknown cause or familial nephropathy or hypertension have diagnostic mutations, which can be identified with whole-exome sequencing (WES), according ...

Diseases, Conditions, Syndromes

Early diagnostic imaging to prevent kidney disease

Osaka University researchers, in collaboration with several Japanese companies, translate neuroimaging tools to study renal fibrosis in rat kidney. The technique is expected to replace the invasive biopsies currently used ...

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